Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

Corticobasal degeneration (CBD) is a neurodegenerative disorder affecting movement and cognition, definitively diagnosed only at autopsy. Here, we conduct a genome-wide association study (GWAS) in CBD cases (n=152) and 3,311 controls, and 67 CBD cases and 439 controls in a replication stage. Associa...

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Detalles Bibliográficos
Autores principales: Kouri, Naomi, Ross, Owen A., Dombroski, Beth, Younkin, Curtis S., Serie, Daniel J., Soto-Ortolaza, Alexandra, Baker, Matthew, Finch, Ni Cole A., Yoon, Hyejin, Kim, Jungsu, Fujioka, Shinsuke, McLean, Catriona A., Ghetti, Bernardino, Spina, Salvatore, Cantwell, Laura B., Farlow, Martin R., Grafman, Jordan, Huey, Edward D., Ryung Han, Mi, Beecher, Sherry, Geller, Evan T., Kretzschmar, Hans A., Roeber, Sigrun, Gearing, Marla, Juncos, Jorge L., Vonsattel, Jean Paul G., Van Deerlin, Vivianna M., Grossman, Murray, Hurtig, Howard I., Gross, Rachel G., Arnold, Steven E., Trojanowski, John Q., Lee, Virginia M., Wenning, Gregor K., White, Charles L., Höglinger, Günter U., Müller, Ulrich, Devlin, Bernie, Golbe, Lawrence I., Crook, Julia, Parisi, Joseph E., Boeve, Bradley F., Josephs, Keith A., Wszolek, Zbigniew K., Uitti, Ryan J., Graff-Radford, Neill R., Litvan, Irene, Younkin, Steven G., Wang, Li-San, Ertekin-Taner, Nilüfer, Rademakers, Rosa, Hakonarsen, Hakon, Schellenberg, Gerard D., Dickson, Dennis W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469997/
https://www.ncbi.nlm.nih.gov/pubmed/26077951
http://dx.doi.org/10.1038/ncomms8247

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