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Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report

Gouty arthritis is uncommon in childhood and adolescence. On the other hand, there has been no report of cases with development of gouty arthritis with post-streptococcal acute glomerulonephritis (PSAGN) in pediatric patients. Here we report the case of a mildly obese 12-year-old boy with PSAGN comp...

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Autores principales: Kuniyoshi, Yasutaka, Kamura, Azusa, Yasuda, Sumie, Tashiro, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470030/
https://www.ncbi.nlm.nih.gov/pubmed/26080801
http://dx.doi.org/10.1186/s12969-015-0019-7
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author Kuniyoshi, Yasutaka
Kamura, Azusa
Yasuda, Sumie
Tashiro, Makoto
author_facet Kuniyoshi, Yasutaka
Kamura, Azusa
Yasuda, Sumie
Tashiro, Makoto
author_sort Kuniyoshi, Yasutaka
collection PubMed
description Gouty arthritis is uncommon in childhood and adolescence. On the other hand, there has been no report of cases with development of gouty arthritis with post-streptococcal acute glomerulonephritis (PSAGN) in pediatric patients. Here we report the case of a mildly obese 12-year-old boy with PSAGN complicated by gouty arthritis of the left first metatarsophalangeal joint. On follow-up, it was confirmed that as serum C3 level returned to normal, urinary excretion of uric acid increased and serum uric acid level decreased, thereby resolving the burning pain of the left big toe. In this case, not only did renal insufficiency associate with PSAGN but also mild obesity may have led to hyperuricemia and gouty arthritis. In conclusion, clinicians should be aware that PSAGN may be complicated by gouty arthritis in obese pediatric patients.
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spelling pubmed-44700302015-06-18 Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report Kuniyoshi, Yasutaka Kamura, Azusa Yasuda, Sumie Tashiro, Makoto Pediatr Rheumatol Online J Case Report Gouty arthritis is uncommon in childhood and adolescence. On the other hand, there has been no report of cases with development of gouty arthritis with post-streptococcal acute glomerulonephritis (PSAGN) in pediatric patients. Here we report the case of a mildly obese 12-year-old boy with PSAGN complicated by gouty arthritis of the left first metatarsophalangeal joint. On follow-up, it was confirmed that as serum C3 level returned to normal, urinary excretion of uric acid increased and serum uric acid level decreased, thereby resolving the burning pain of the left big toe. In this case, not only did renal insufficiency associate with PSAGN but also mild obesity may have led to hyperuricemia and gouty arthritis. In conclusion, clinicians should be aware that PSAGN may be complicated by gouty arthritis in obese pediatric patients. BioMed Central 2015-06-17 /pmc/articles/PMC4470030/ /pubmed/26080801 http://dx.doi.org/10.1186/s12969-015-0019-7 Text en © Kuniyoshi et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Kuniyoshi, Yasutaka
Kamura, Azusa
Yasuda, Sumie
Tashiro, Makoto
Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report
title Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report
title_full Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report
title_fullStr Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report
title_full_unstemmed Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report
title_short Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report
title_sort post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470030/
https://www.ncbi.nlm.nih.gov/pubmed/26080801
http://dx.doi.org/10.1186/s12969-015-0019-7
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