Lipoic acid decreases Mcl-1, Bcl-x(L) and up regulates Bim on ovarian carcinoma cells leading to cell death

BACKGROUND: Ovarian carcinoma is the leading cause of death from gynecological cancer because there is risk of chemoresistance. As previously demonstrated in our laboratory, Alpha-lipoic acid (LA), a co-factor for metabolic enzymes, suppresses the tumor growth. In this study, we have researched the...

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Detalles Bibliográficos
Autores principales: Kafara, Perrine, Icard, Philippe, Guillamin, Marilyne, Schwartz, Laurent, Lincet, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470044/
https://www.ncbi.nlm.nih.gov/pubmed/26063499
http://dx.doi.org/10.1186/s13048-015-0165-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470044/
https://www.ncbi.nlm.nih.gov/pubmed/26063499
http://dx.doi.org/10.1186/s13048-015-0165-z

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