Transient blocking of NK cell function with small molecule inhibitors for helper dependant adenoviral vector-mediated gene delivery

One major challenge in gene therapy is the host immune responses against viral vectors. Previous studies indicate the involvement of NK cells in stunted gene expression in viral vector mediated gene therapy. To understand the problem of the immune responses, we have developed an in-vitro co-culture...

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Detalles Bibliográficos
Autores principales: Ankathatti Munegowda, Manjunatha, Hu, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470062/
https://www.ncbi.nlm.nih.gov/pubmed/26085921
http://dx.doi.org/10.1186/s13578-015-0023-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470062/
https://www.ncbi.nlm.nih.gov/pubmed/26085921
http://dx.doi.org/10.1186/s13578-015-0023-0

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