Cargando…
Transient blocking of NK cell function with small molecule inhibitors for helper dependant adenoviral vector-mediated gene delivery
One major challenge in gene therapy is the host immune responses against viral vectors. Previous studies indicate the involvement of NK cells in stunted gene expression in viral vector mediated gene therapy. To understand the problem of the immune responses, we have developed an in-vitro co-culture...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470062/ https://www.ncbi.nlm.nih.gov/pubmed/26085921 http://dx.doi.org/10.1186/s13578-015-0023-0 |