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Review of Tolvaptan’s Pharmacokinetic and Pharmacodynamic Properties and Drug Interactions

Tolvaptan is an arginine vasopressin (AVP) antagonist that acts to increase excretion of free water (aquaresis) in patients without introducing electrolyte abnormalities or worsening renal function. It works via blockade of vasopressin-2 receptors at the renal collecting duct. Since the approval of...

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Detalles Bibliográficos
Autores principales:	Bhatt, Purav R., McNeely, Elizabeth B., Lin, Tess E., Adams, Kirkwood F., Patterson, J. Herbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470182/ https://www.ncbi.nlm.nih.gov/pubmed/26237603 http://dx.doi.org/10.3390/jcm3041276

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