Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism

We report a case of a previously undiagnosed panhypopituitarism initially presenting as a full-blown Addisonian crisis with hypoglycemia, hyponatremia, hypotension and neuropsychological symptoms, more than 30 years after a severe traumatic brain injury (TBI). The patient also displayed clearly visi...

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Autores principales: Streetz-van der Werf, Christine, Karges, Wolfram, Blaum, Marcus, Kreitschmann-Andermahr, Ilonka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470209/
https://www.ncbi.nlm.nih.gov/pubmed/26239458
http://dx.doi.org/10.3390/jcm4050965
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author Streetz-van der Werf, Christine
Karges, Wolfram
Blaum, Marcus
Kreitschmann-Andermahr, Ilonka
author_facet Streetz-van der Werf, Christine
Karges, Wolfram
Blaum, Marcus
Kreitschmann-Andermahr, Ilonka
author_sort Streetz-van der Werf, Christine
collection PubMed
description We report a case of a previously undiagnosed panhypopituitarism initially presenting as a full-blown Addisonian crisis with hypoglycemia, hyponatremia, hypotension and neuropsychological symptoms, more than 30 years after a severe traumatic brain injury (TBI). The patient also displayed clearly visible pathognomonic clinical signs of long-standing pituitary dysfunction. The case highlights the importance of being aware of endocrine sequelae even decades after serious TBI.
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spelling pubmed-44702092015-07-28 Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism Streetz-van der Werf, Christine Karges, Wolfram Blaum, Marcus Kreitschmann-Andermahr, Ilonka J Clin Med Article We report a case of a previously undiagnosed panhypopituitarism initially presenting as a full-blown Addisonian crisis with hypoglycemia, hyponatremia, hypotension and neuropsychological symptoms, more than 30 years after a severe traumatic brain injury (TBI). The patient also displayed clearly visible pathognomonic clinical signs of long-standing pituitary dysfunction. The case highlights the importance of being aware of endocrine sequelae even decades after serious TBI. MDPI 2015-05-15 /pmc/articles/PMC4470209/ /pubmed/26239458 http://dx.doi.org/10.3390/jcm4050965 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Streetz-van der Werf, Christine
Karges, Wolfram
Blaum, Marcus
Kreitschmann-Andermahr, Ilonka
Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism
title Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism
title_full Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism
title_fullStr Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism
title_full_unstemmed Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism
title_short Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism
title_sort addisonian crisis after missed diagnosis of posttraumatic hypopituitarism
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470209/
https://www.ncbi.nlm.nih.gov/pubmed/26239458
http://dx.doi.org/10.3390/jcm4050965
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