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Mathematical modelling of the automated FADU assay for the quantification of DNA strand breaks and their repair in human peripheral mononuclear blood cells

BACKGROUND: Cells continuously undergo DNA damage from exogenous agents like irradiation or genotoxic chemicals or from endogenous radicals produced by normal cellular metabolic activities. DNA strand breaks are one of the most common genotoxic lesions and they can also arise as intermediates of DNA...

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Detalles Bibliográficos
Autores principales:	Junk, Michael, Salzwedel, Judy, Sindlinger, Thilo, Bürkle, Alexander, Moreno-Villanueva, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470348/ https://www.ncbi.nlm.nih.gov/pubmed/26085926 http://dx.doi.org/10.1186/s13628-014-0009-z

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