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Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor

Lentiviral vectors are widely used in the field of gene therapy as an effective method for permanent gene delivery. While current methods of producing small scale vector batches for research purposes depend largely on culture flasks, the emergence and popularity of lentiviral vectors in translationa...

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Detalles Bibliográficos
Autores principales: Sheu, Jonathan, Beltzer, Jim, Fury, Brian, Wilczek, Katarzyna, Tobin, Steve, Falconer, Danny, Nolta, Jan, Bauer, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470365/
https://www.ncbi.nlm.nih.gov/pubmed/26151065
http://dx.doi.org/10.1038/mtm.2015.20

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