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Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor
Lentiviral vectors are widely used in the field of gene therapy as an effective method for permanent gene delivery. While current methods of producing small scale vector batches for research purposes depend largely on culture flasks, the emergence and popularity of lentiviral vectors in translationa...
Autores principales: | Sheu, Jonathan, Beltzer, Jim, Fury, Brian, Wilczek, Katarzyna, Tobin, Steve, Falconer, Danny, Nolta, Jan, Bauer, Gerhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470365/ https://www.ncbi.nlm.nih.gov/pubmed/26151065 http://dx.doi.org/10.1038/mtm.2015.20 |
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