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Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance
Staphylococcus aureus infections exert a tremendous burden on the health-care system, and the threat of drug-resistant strains continues to grow. The bacteriolytic enzyme lysostaphin is a potent antistaphylococcal agent with proven efficacy against both drug-sensitive and drug-resistant strains; how...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470366/ https://www.ncbi.nlm.nih.gov/pubmed/26151066 http://dx.doi.org/10.1038/mtm.2015.21 |