KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas

Up to 20% of patients with pilocytic astrocytoma (PA) experience a poor outcome. BRAF alterations and Fibroblast growth factor receptor 1 (FGFR1) point mutations are key molecular alterations in Pas, but their clinical implications are not established. We aimed to determine the frequency and prognos...

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Detalles Bibliográficos
Autores principales: Becker, Aline Paixão, Scapulatempo-Neto, Cristovam, Carloni, Adriana C., Paulino, Alessandra, Sheren, Jamie, Aisner, Dara L., Musselwhite, Evelyn, Clara, Carlos, Machado, Hélio R., Oliveira, Ricardo S., Neder, Luciano, Varella-Garcia, Marileila, Reis, Rui M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neuropathologists 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470527/
https://www.ncbi.nlm.nih.gov/pubmed/26083571
http://dx.doi.org/10.1097/NEN.0000000000000213

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