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Pareto Optimization Identifies Diverse Set of Phosphorylation Signatures Predicting Response to Treatment with Dasatinib
Multivariate biomarkers that can predict the effectiveness of targeted therapy in individual patients are highly desired. Previous biomarker discovery studies have largely focused on the identification of single biomarker signatures, aimed at maximizing prediction accuracy. Here, we present a differ...
Autores principales: | Klammer, Martin, Dybowski, J. Nikolaj, Hoffmann, Daniel, Schaab, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470654/ https://www.ncbi.nlm.nih.gov/pubmed/26083411 http://dx.doi.org/10.1371/journal.pone.0128542 |
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