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Pareto Optimization Identifies Diverse Set of Phosphorylation Signatures Predicting Response to Treatment with Dasatinib

Multivariate biomarkers that can predict the effectiveness of targeted therapy in individual patients are highly desired. Previous biomarker discovery studies have largely focused on the identification of single biomarker signatures, aimed at maximizing prediction accuracy. Here, we present a differ...

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Detalles Bibliográficos
Autores principales: Klammer, Martin, Dybowski, J. Nikolaj, Hoffmann, Daniel, Schaab, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470654/
https://www.ncbi.nlm.nih.gov/pubmed/26083411
http://dx.doi.org/10.1371/journal.pone.0128542

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