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Role of Glutathione Peroxidase 4 in Glutamate-Induced Oxytosis in the Retina

PURPOSE: The purpose of the present study was to investigate the role of glutathione peroxidase 4 (GPx4) in glutamate-induced oxytosis in the retina. METHODS: For in vitro studies, an immortalized rat retinal precursor cell line R28 was used. Cells were transfected with siRNA specifically silencing...

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Detalles Bibliográficos
Autores principales: Sakai, Osamu, Uchida, Takatoshi, Roggia, Murilo F., Imai, Hirotaka, Ueta, Takashi, Amano, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470664/
https://www.ncbi.nlm.nih.gov/pubmed/26083388
http://dx.doi.org/10.1371/journal.pone.0130467