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Computational and Biochemical Discovery of RSK2 as a Novel Target for Epigallocatechin Gallate (EGCG)
The most active anticancer component in green tea is epigallocatechin-3-gallate (EGCG). Protein interaction with EGCG is a critical step for mediating the effects of EGCG on the regulation of various key molecules involved in signal transduction. By using computational docking screening methods for...
Autores principales: | Chen, Hanyong, Yao, Ke, Chang, Xiaoyu, Shim, Jung-Hyun, Kim, Hong-Gyum, Malakhova, Margarita, Kim, Dong-Joon, Bode, Ann M., Dong, Zigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470687/ https://www.ncbi.nlm.nih.gov/pubmed/26083344 http://dx.doi.org/10.1371/journal.pone.0130049 |
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