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The Receptor for Advanced Glycation End Products (RAGE) Enhances Autophagy and Neutrophil Extracellular Traps in Pancreatic Cancer
Neutrophil extracellular traps (NETs) are formed when neutrophils expel their DNA, histones and intracellular proteins into the extracellular space or circulation. NET formation is dependent on autophagy and is mediated by citrullination of histones to allow for unwinding and subsequent expulsion of...
Autores principales: | Boone, Brian A., Orlichenko, Lidiya, Schapiro, Nicole E., Loughran, Patricia, Gianfrate, Gianmarino C., Ellis, Jarrod T., Singhi, Aatur D., Kang, Rui, Tang, Daolin, Lotze, Michael T., Zeh, Herbert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470814/ https://www.ncbi.nlm.nih.gov/pubmed/25908451 http://dx.doi.org/10.1038/cgt.2015.21 |
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