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Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells

Pseudomonas aeruginosa infection can be disastrous in chronic lung diseases such as cystic fibrosis and chronic obstructive pulmonary disease. Its toxic effects are largely mediated by secreted virulence factors including pyocyanin, elastase and alkaline protease (AprA). Efficient functioning of the...

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Detalles Bibliográficos
Autores principales: van ‘t Wout, Emily F. A., van Schadewijk, Annemarie, van Boxtel, Ria, Dalton, Lucy E., Clarke, Hanna J., Tommassen, Jan, Marciniak, Stefan J., Hiemstra, Pieter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471080/
https://www.ncbi.nlm.nih.gov/pubmed/26083346
http://dx.doi.org/10.1371/journal.ppat.1004946

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