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Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells
Pseudomonas aeruginosa infection can be disastrous in chronic lung diseases such as cystic fibrosis and chronic obstructive pulmonary disease. Its toxic effects are largely mediated by secreted virulence factors including pyocyanin, elastase and alkaline protease (AprA). Efficient functioning of the...
Autores principales: | van ‘t Wout, Emily F. A., van Schadewijk, Annemarie, van Boxtel, Ria, Dalton, Lucy E., Clarke, Hanna J., Tommassen, Jan, Marciniak, Stefan J., Hiemstra, Pieter S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471080/ https://www.ncbi.nlm.nih.gov/pubmed/26083346 http://dx.doi.org/10.1371/journal.ppat.1004946 |
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