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Lipid peroxidation is essential for α‐synuclein‐induced cell death

Parkinson's disease is the second most common neurodegenerative disease and its pathogenesis is closely associated with oxidative stress. Deposition of aggregated α‐synuclein (α‐Syn) occurs in familial and sporadic forms of Parkinson's disease. Here, we studied the effect of oligomeric α‐S...

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Detalles Bibliográficos
Autores principales: Angelova, Plamena R., Horrocks, Mathew H., Klenerman, David, Gandhi, Sonia, Abramov, Andrey Y., Shchepinov, Mikhail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471127/
https://www.ncbi.nlm.nih.gov/pubmed/25580849
http://dx.doi.org/10.1111/jnc.13024

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