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Neurocognitive dysfunction and pharmacological intervention using guanfacine in a rhesus macaque model of self-injurious behavior
Self-injurious behavior (SIB) is a common comorbidity of psychiatric disorders but there is a dearth of information about neurological mechanisms underlying the behavior, and few animal models exist. SIB in humans is characterized by any intentional self-directed behavior that leads to wounds, where...
Autores principales: | Freeman, Z T, Rice, K A, Soto, P L, Pate, K A M, Weed, M R, Ator, N A, DeLeon, I G, Wong, D F, Zhou, Y, Mankowski, J L, Zink, M C, Adams, R J, Hutchinson, E K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471292/ https://www.ncbi.nlm.nih.gov/pubmed/25989141 http://dx.doi.org/10.1038/tp.2015.61 |
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