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Adaptive Immunity and Antigen-Specific Activation in Obesity-Associated Insulin Resistance

Type 2 diabetes mellitus (T2D) is a metabolic disease that is strongly tied to obesity and often preceded by insulin resistance (IR). It has been established that chronic inflammation of hypertrophic adipose tissue depots in obese individuals leads to obesity-associated IR and is mediated by cells o...

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Detalles Bibliográficos
Autores principales: Chng, Melissa Hui Yen, Alonso, Michael N., Barnes, Sarah E., Nguyen, Khoa D., Engleman, Edgar G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471324/
https://www.ncbi.nlm.nih.gov/pubmed/26146464
http://dx.doi.org/10.1155/2015/593075