Palladium(II)/Brønsted Acid-Catalyzed Enantioselective Oxidative Carbocyclization–Borylation of Enallenes**

An enantioselective oxidative carbocyclization–borylation of enallenes that is catalyzed by palladium(II) and a Brønsted acid was developed. Biphenol-type chiral phosphoric acids were superior co-catalysts for inducing the enantioselective cyclization. A number of chiral borylated carbocycles were s...

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Detalles Bibliográficos
Autores principales: Jiang, Tuo, Bartholomeyzik, Teresa, Mazuela, Javier, Willersinn, Jochen, Bäckvall, Jan-E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471548/
https://www.ncbi.nlm.nih.gov/pubmed/25808996
http://dx.doi.org/10.1002/anie.201501048
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author Jiang, Tuo
Bartholomeyzik, Teresa
Mazuela, Javier
Willersinn, Jochen
Bäckvall, Jan-E
author_facet Jiang, Tuo
Bartholomeyzik, Teresa
Mazuela, Javier
Willersinn, Jochen
Bäckvall, Jan-E
author_sort Jiang, Tuo
collection PubMed
description An enantioselective oxidative carbocyclization–borylation of enallenes that is catalyzed by palladium(II) and a Brønsted acid was developed. Biphenol-type chiral phosphoric acids were superior co-catalysts for inducing the enantioselective cyclization. A number of chiral borylated carbocycles were synthesized in high enantiomeric excess.
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spelling pubmed-44715482015-06-23 Palladium(II)/Brønsted Acid-Catalyzed Enantioselective Oxidative Carbocyclization–Borylation of Enallenes** Jiang, Tuo Bartholomeyzik, Teresa Mazuela, Javier Willersinn, Jochen Bäckvall, Jan-E Angew Chem Int Ed Engl Communications An enantioselective oxidative carbocyclization–borylation of enallenes that is catalyzed by palladium(II) and a Brønsted acid was developed. Biphenol-type chiral phosphoric acids were superior co-catalysts for inducing the enantioselective cyclization. A number of chiral borylated carbocycles were synthesized in high enantiomeric excess. WILEY-VCH Verlag 2015-05-11 2015-03-24 /pmc/articles/PMC4471548/ /pubmed/25808996 http://dx.doi.org/10.1002/anie.201501048 Text en © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the terms of the Creative Commons Attribution Non-Commercial NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Communications
Jiang, Tuo
Bartholomeyzik, Teresa
Mazuela, Javier
Willersinn, Jochen
Bäckvall, Jan-E
Palladium(II)/Brønsted Acid-Catalyzed Enantioselective Oxidative Carbocyclization–Borylation of Enallenes**
title Palladium(II)/Brønsted Acid-Catalyzed Enantioselective Oxidative Carbocyclization–Borylation of Enallenes**
title_full Palladium(II)/Brønsted Acid-Catalyzed Enantioselective Oxidative Carbocyclization–Borylation of Enallenes**
title_fullStr Palladium(II)/Brønsted Acid-Catalyzed Enantioselective Oxidative Carbocyclization–Borylation of Enallenes**
title_full_unstemmed Palladium(II)/Brønsted Acid-Catalyzed Enantioselective Oxidative Carbocyclization–Borylation of Enallenes**
title_short Palladium(II)/Brønsted Acid-Catalyzed Enantioselective Oxidative Carbocyclization–Borylation of Enallenes**
title_sort palladium(ii)/brønsted acid-catalyzed enantioselective oxidative carbocyclization–borylation of enallenes**
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471548/
https://www.ncbi.nlm.nih.gov/pubmed/25808996
http://dx.doi.org/10.1002/anie.201501048
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