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Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System Demyelination

Clostridium perfringens epsilon toxin (ε-toxin) is responsible for a devastating multifocal central nervous system (CNS) white matter disease in ruminant animals. The mechanism by which ε-toxin causes white matter damage is poorly understood. In this study, we sought to determine the molecular and c...

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Detalles Bibliográficos
Autores principales: Linden, Jennifer R., Ma, Yinghua, Zhao, Baohua, Harris, Jason Michael, Rumah, Kareem Rashid, Schaeren-Wiemers, Nicole, Vartanian, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471556/
https://www.ncbi.nlm.nih.gov/pubmed/26081637
http://dx.doi.org/10.1128/mBio.02513-14