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Combinatorial Library Based Engineering of Candida antarctica Lipase A for Enantioselective Transacylation of sec-Alcohols in Organic Solvent**

A method for determining lipase enantioselectivity in the transacylation of sec-alcohols in organic solvent was developed. The method was applied to a model library of Candida antarctica lipase A (CalA) variants for improved enantioselectivity (E values) in the kinetic resolution of 1-phenylethanol...

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Detalles Bibliográficos
Autores principales:	Wikmark, Ylva, Svedendahl Humble, Maria, Bäckvall, Jan-E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2015
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471580/ https://www.ncbi.nlm.nih.gov/pubmed/25676632 http://dx.doi.org/10.1002/anie.201410675

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