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Extraction and elemental analysis of Coleus forskohlii extract

BACKGROUND: Coleus forskohlii Willd. is a popular traditional medicine used since ancient times for treatment of heart diseases, abdominal colic and respiratory disorders. OBJECTIVE: The aim of this study was to characterize the root extract of the medicinal plant Coleus forskohlii. MATERIALS AND ME...

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Autores principales: Kanne, Haritha, Burte, Narayan Pandurang, Prasanna, V., Gujjula, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471649/
https://www.ncbi.nlm.nih.gov/pubmed/26130934
http://dx.doi.org/10.4103/0974-8490.157966
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author Kanne, Haritha
Burte, Narayan Pandurang
Prasanna, V.
Gujjula, Ravi
author_facet Kanne, Haritha
Burte, Narayan Pandurang
Prasanna, V.
Gujjula, Ravi
author_sort Kanne, Haritha
collection PubMed
description BACKGROUND: Coleus forskohlii Willd. is a popular traditional medicine used since ancient times for treatment of heart diseases, abdominal colic and respiratory disorders. OBJECTIVE: The aim of this study was to characterize the root extract of the medicinal plant Coleus forskohlii. MATERIALS AND METHODS: Dry roots of C. forskohlii were used to extract Forskolin using toluene as a solvent. Thus, obtained extract of C. forskohlii was standardized to 30% and used for further studies. RESULTS: The physical properties of the extract were analyzed through scanning electron microscopy analysis, while the characterization of root extract through X-ray diffraction (XRD) and element analysis. The morphological feature of the C. forskohlii extract showed a flake like structure and the XRD showed sulfur trioxide (SO(3)) and trimer of sulfur trioxide (S(3) O(9)). Through element analysis, elements such as carbon, oxygen, magnesium, aluminum, silicon, phosphorous, and sulfur were identified. Carbon showed the highest weight of 75.49% in comparison to all other elements.
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spelling pubmed-44716492015-07-01 Extraction and elemental analysis of Coleus forskohlii extract Kanne, Haritha Burte, Narayan Pandurang Prasanna, V. Gujjula, Ravi Pharmacognosy Res Original Article BACKGROUND: Coleus forskohlii Willd. is a popular traditional medicine used since ancient times for treatment of heart diseases, abdominal colic and respiratory disorders. OBJECTIVE: The aim of this study was to characterize the root extract of the medicinal plant Coleus forskohlii. MATERIALS AND METHODS: Dry roots of C. forskohlii were used to extract Forskolin using toluene as a solvent. Thus, obtained extract of C. forskohlii was standardized to 30% and used for further studies. RESULTS: The physical properties of the extract were analyzed through scanning electron microscopy analysis, while the characterization of root extract through X-ray diffraction (XRD) and element analysis. The morphological feature of the C. forskohlii extract showed a flake like structure and the XRD showed sulfur trioxide (SO(3)) and trimer of sulfur trioxide (S(3) O(9)). Through element analysis, elements such as carbon, oxygen, magnesium, aluminum, silicon, phosphorous, and sulfur were identified. Carbon showed the highest weight of 75.49% in comparison to all other elements. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4471649/ /pubmed/26130934 http://dx.doi.org/10.4103/0974-8490.157966 Text en Copyright: © Pharmacognosy Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kanne, Haritha
Burte, Narayan Pandurang
Prasanna, V.
Gujjula, Ravi
Extraction and elemental analysis of Coleus forskohlii extract
title Extraction and elemental analysis of Coleus forskohlii extract
title_full Extraction and elemental analysis of Coleus forskohlii extract
title_fullStr Extraction and elemental analysis of Coleus forskohlii extract
title_full_unstemmed Extraction and elemental analysis of Coleus forskohlii extract
title_short Extraction and elemental analysis of Coleus forskohlii extract
title_sort extraction and elemental analysis of coleus forskohlii extract
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471649/
https://www.ncbi.nlm.nih.gov/pubmed/26130934
http://dx.doi.org/10.4103/0974-8490.157966
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