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Mannan-modified adenovirus targeting TERT and VEGFR-2: A universal tumour vaccine
Antigen-presenting cells including dendritic cells (DCs) express mannan receptors (MR) on their surface, which can be exploited in cancer therapy by designing immune-stimulatory viruses coated with mannan-modified capsids that then bind to DCs and initiate a potent immune response. Although the comb...
Autores principales: | Wang, Ying, Zhang, Jie, Wu, Yang, Ding, Zhen-Yu, Luo, Xin-Mei, Liu, Jie, Zhong, Wu-Ning, Deng, Guo-Hua, Xia, Xiang-Yu, Deng, Yao-Tiao, Wei, Yu-Quan, Jiang, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471666/ https://www.ncbi.nlm.nih.gov/pubmed/26085010 http://dx.doi.org/10.1038/srep11275 |
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