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A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis
Neutrophils contain granules loaded with antimicrobial proteins and are regarded as impermeable organelles that deliver cargo via membrane fusion. However, during the formation of neutrophil extracellular traps (NETs), neutrophil elastase (NE) translocates from the granules to the nucleus via an unk...
Autores principales: | Metzler, Kathleen D., Goosmann, Christian, Lubojemska, Aleksandra, Zychlinsky, Arturo, Papayannopoulos, Venizelos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471680/ https://www.ncbi.nlm.nih.gov/pubmed/25066128 http://dx.doi.org/10.1016/j.celrep.2014.06.044 |
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