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Diverse involvement of isoforms and gene aberrations of Akt in human lung carcinomas

Emerging evidence confirms a central role of Akt in cancer. To evaluate the relative contribution of deregulated Akt and their clinicopathological significance in lung carcinomas, overexpression, activation of Akt and AKT gene increases were investigated. Immunohistochemical staining for 108 cases r...

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Detalles Bibliográficos
Autores principales: Dobashi, Yoh, Tsubochi, Hiroyoshi, Matsubara, Hirochika, Inoue, Jun, Inazawa, Johji, Endo, Shunsuke, Ooi, Akishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471790/
https://www.ncbi.nlm.nih.gov/pubmed/25855050
http://dx.doi.org/10.1111/cas.12669