Cargando…

IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages

Interferon Regulatory Factor 5 (IRF5) plays a major role in setting up an inflammatory macrophage phenotype, but the molecular basis of its transcriptional activity is not fully understood. In this study, we conduct a comprehensive genome-wide analysis of IRF5 recruitment in macrophages stimulated w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saliba, David G., Heger, Andreas, Eames, Hayley L., Oikonomopoulos, Spyros, Teixeira, Ana, Blazek, Katrina, Androulidaki, Ariadne, Wong, Daniel, Goh, Fui G., Weiss, Miriam, Byrne, Adam, Pasparakis, Manolis, Ragoussis, Jiannis, Udalova, Irina A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2014
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471814/ https://www.ncbi.nlm.nih.gov/pubmed/25159141 http://dx.doi.org/10.1016/j.celrep.2014.07.034

Ejemplares similares

NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer
por: Koerner, Lioba, et al.
Publicado: (2023)

Cross-species Analysis Reveals Evolving and Conserved Features of the Nuclear Factor κB (NF-κB) Proteins
por: Ryzhakov, Grigory, et al.
Publicado: (2013)

A critical role for IRF5 in regulating allergic airway inflammation
por: Byrne, Adam J., et al.
Publicado: (2016)

Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes
por: Androulidaki, Ariadne, et al.
Publicado: (2018)

Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams
por: Kudrin, Pavel, et al.
Publicado: (2017)

IRF5 Is a Specific Marker of Inflammatory Macrophages In Vivo
por: Weiss, Miriam, et al.
Publicado: (2013)

Influence of the relA gene on ribosome frameshifting
por: Masucci, J., et al.
Publicado: (2002)

Identification of genes responsible for RelA-dependent proliferation arrest in human mammary epithelial cells conditionally expressing RelA
por: Kochupurakkal, Bose S., et al.
Publicado: (2015)

NF-κB/Rel Transcription Factors in Pancreatic Cancer: Focusing on RelA, c-Rel, and RelB
por: Kabacaoglu, Derya, et al.
Publicado: (2019)

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits
por: Wong, Daniel, et al.
Publicado: (2011)

Improved Nanopore full-length cDNA sequencing by PCR-suppression
por: Bayega, Anthony, et al.
Publicado: (2022)

relA Enhances the Adherence of Enteropathogenic Escherichia coli
por: Spira, Beny, et al.
Publicado: (2014)

relA Inactivation Converts Sulfonamides Into Bactericidal Compounds
por: Si, Lizhen, et al.
Publicado: (2021)

NirD curtails the stringent response by inhibiting RelA activity in Escherichia coli
por: Léger, Loïc, et al.
Publicado: (2021)

The Role of relA and spoT in Yersinia pestis KIM5(+) Pathogenicity
por: Sun, Wei, et al.
Publicado: (2009)

RelA-Induced Interferon Response Negatively Regulates Proliferation
por: Kochupurakkal, Bose S., et al.
Publicado: (2015)

Benchmarking of the Oxford Nanopore MinION sequencing for quantitative and qualitative assessment of cDNA populations
por: Oikonomopoulos, Spyros, et al.
Publicado: (2016)

Methodologies for Transcript Profiling Using Long-Read Technologies
por: Oikonomopoulos, Spyros, et al.
Publicado: (2020)

Ribosome•RelA structures reveal the mechanism of stringent response activation
por: Loveland, Anna B, et al.
Publicado: (2016)

Effects of Human RelA Transgene on Murine Macrophage Inflammatory Responses
por: Papoutsopoulou, Stamatia, et al.
Publicado: (2022)

relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells
por: Ricca, A, et al.
Publicado: (2001)

Differential RelA- and RelB-dependent gene transcription in LTβR-stimulated mouse embryonic fibroblasts
por: Lovas, Agnes, et al.
Publicado: (2008)

NF-κB Repression by PIAS3 Mediated RelA SUMOylation
por: Liu, Yuangang, et al.
Publicado: (2012)

Biochemical studies on Francisella tularensis RelA in (p)ppGpp biosynthesis
por: Wilkinson, Rachael C., et al.
Publicado: (2015)

RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host
por: Honsa, Erin S., et al.
Publicado: (2017)

Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor
por: Beljantseva, Jelena, et al.
Publicado: (2017)

Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA
por: Turnbull, Kathryn Jane, et al.
Publicado: (2019)

Escherichia coli RelA Regulation via Its C-Terminal Domain
por: Kaspy, Ilana, et al.
Publicado: (2020)

Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination
por: Li, Haiying, et al.
Publicado: (2011)

Deletion of relA abrogates the capacity of Mycobacterium avium paratuberculosis to establish an infection in calves
por: Park, Kun Taek, et al.
Publicado: (2014)

A Comparative Proteome Analysis of Escherichia coli ΔrelA Mutant Cells
por: Carneiro, Sónia, et al.
Publicado: (2016)

The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA
por: Kudrin, Pavel, et al.
Publicado: (2018)

Deubiquitinylase USP47 Promotes RelA Phosphorylation and Survival in Gastric Cancer Cells
por: Naghavi, Lara, et al.
Publicado: (2018)

Identification of a Selective RelA Inhibitor Based on DSE-FRET Screening Methods
por: Shiroma, Yoshitomo, et al.
Publicado: (2020)

Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation
por: Li, Yunlong, et al.
Publicado: (2023)

Influence of the RelA Activity on E. coli Metabolism by Metabolite Profiling of Glucose-Limited Chemostat Cultures
por: Carneiro, Sónia, et al.
Publicado: (2012)

Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation
por: Oikonomou, Nikos, et al.
Publicado: (2021)

Differential expression of NF-κB heterodimer RelA/p50 in human urothelial carcinoma
por: Durairajan, Sankari, et al.
Publicado: (2018)

Listeria monocytogenes Infection in Macrophages Induces Vacuolar-Dependent Host miRNA Response
por: Schnitger, Anna K. D., et al.
Publicado: (2011)

Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid Organs
por: Alcamo, Elizabeth, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_9fqjopq2oclnfi4q998ukgu6bm