Cargando…

TeratoScore: Assessing the Differentiation Potential of Human Pluripotent Stem Cells by Quantitative Expression Analysis of Teratomas

Teratoma formation is the gold standard assay for testing the capacity of human pluripotent stem cells to differentiate into all embryonic germ layers. Although widely used, little effort has been made to transform this qualitative assay into a quantitative one. Using gene expression data from a wid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Avior, Yishai, Biancotti, Juan Carlos, Benvenisty, Nissim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471824/ https://www.ncbi.nlm.nih.gov/pubmed/26070610 http://dx.doi.org/10.1016/j.stemcr.2015.05.006

Ejemplares similares

Modeling Developmental and Tumorigenic Aspects of Trilateral Retinoblastoma via Human Embryonic Stem Cells
por: Avior, Yishai, et al.
Publicado: (2017)

The Chromatin Regulator ZMYM2 Restricts Human Pluripotent Stem Cell Growth and Is Essential for Teratoma Formation
por: Lezmi, Elyad, et al.
Publicado: (2020)

The Tumorigenic Potential of Human Pluripotent Stem Cells
por: Lezmi, Elyad, et al.
Publicado: (2022)

Molecular Characterization of Down Syndrome Embryonic Stem Cells Reveals a Role for RUNX1 in Neural Differentiation
por: Halevy, Tomer, et al.
Publicado: (2016)

Genome maintenance in pluripotent stem cells
por: Weissbein, Uri, et al.
Publicado: (2014)

Large-scale analysis of imprinting in naive human pluripotent stem cells reveals recurrent aberrations and a potential link to FGF signaling
por: Keshet, Gal, et al.
Publicado: (2021)

Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations
por: Merkle, Florian T., et al.
Publicado: (2017)

Modeling Maturity Onset Diabetes of the Young in Pluripotent Stem Cells: Challenges and Achievements
por: Braverman-Gross, Carmel, et al.
Publicado: (2021)

Human embryonic stem cells from aneuploid blastocysts identified by pre-implantation genetic screening
por: Narwani, Kavita, et al.
Publicado: (2010)

Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells
por: Weissbein, Uri, et al.
Publicado: (2017)

Molecular Mechanisms Regulating the Defects in Fragile X Syndrome Neurons Derived from Human Pluripotent Stem Cells
por: Halevy, Tomer, et al.
Publicado: (2014)

Identification of Novel Imprinted Differentially Methylated Regions by Global Analysis of Human-Parthenogenetic-Induced Pluripotent Stem Cells
por: Stelzer, Yonatan, et al.
Publicado: (2013)

Murine pluripotent stem cells that escape differentiation inside teratomas maintain pluripotency
por: Pei, Yangli, et al.
Publicado: (2018)

Global Indiscriminate Methylation in Cell-Specific Gene Promoters following Reprogramming into Human Induced Pluripotent Stem Cells
por: Nissenbaum, Jonathan, et al.
Publicado: (2013)

Teratogen screening using transcriptome profiling of differentiating human embryonic stem cells
por: Mayshar, Yoav, et al.
Publicado: (2011)

Cisplatin induces differentiation in teratomas derived from pluripotent stem cells
por: Kurata, Atsushi, et al.
Publicado: (2021)

Genome-wide Screen for Culture Adaptation and Tumorigenicity-Related Genes in Human Pluripotent Stem Cells
por: Weissbein, Uri, et al.
Publicado: (2019)

The essentiality landscape of cell cycle related genes in human pluripotent and cancer cells
por: Viner-Breuer, Ruth, et al.
Publicado: (2019)

Generation, genomic characterization, and differentiation of triploid human embryonic stem cells
por: Haim-Abadi, Guy, et al.
Publicado: (2023)

Studying Early Lethality of 45,XO (Turner's Syndrome) Embryos Using Human Embryonic Stem Cells
por: Urbach, Achia, et al.
Publicado: (2009)

Differentiation-Defective Human Induced Pluripotent Stem Cells Reveal Strengths and Limitations of the Teratoma Assay and In Vitro Pluripotency Assays
por: Bouma, Marga J., et al.
Publicado: (2017)

Large-Scale Analysis of X Inactivation Variations between Primed and Naïve Human Embryonic Stem Cells
por: Sarel-Gallily, Roni, et al.
Publicado: (2022)

Reversible transformation and de-differentiation of human cells derived from induced pluripotent stem cell teratomas
por: Kamada, Mizuna, et al.
Publicado: (2015)

Genome-wide loss-of-function screen using human pluripotent stem cells to study virus-host interactions for SARS-CoV-2
por: Pagis, Ariel, et al.
Publicado: (2023)

An improved ScoreCard to assess the differentiation potential of human pluripotent stem cells
por: Tsankov, Alexander M., et al.
Publicado: (2015)

Attenuation of teratoma formation by p27 overexpression in induced pluripotent stem cells
por: Matsu-ura, Toru, et al.
Publicado: (2016)

Defining the Skeletal Myogenic Lineage in Human Pluripotent Stem Cell-Derived Teratomas
por: Pappas, Matthew P., et al.
Publicado: (2022)

Differentiation of uniparental human embryonic stem cells into granulosa cells reveals a paternal contribution to gonadal development
por: Keshet, Gal, et al.
Publicado: (2023)

Increasing Hematopoietic Stem Cell Yield to Develop Mice with Human Immune Systems
por: Biancotti, Juan-Carlos, et al.
Publicado: (2013)

Using Advanced Cell Culture Techniques to Differentiate Pluripotent Stem Cells and Recreate Tissue Structures Representative of Teratoma Xenografts
por: Smith, L. A., et al.
Publicado: (2021)

Immunoreactivity of Pluripotent Markers SSEA-5 and L1CAM in Human Tumors, Teratomas, and Induced Pluripotent Stem Cells
por: Cassidy, Linda, et al.
Publicado: (2013)

Standardization of the Teratoma Assay for Analysis of Pluripotency of Human ES Cells and Biosafety of Their Differentiated Progeny
por: Gropp, Michal, et al.
Publicado: (2012)

Monoclonal antibody K312-based depletion of pluripotent cells from differentiated stem cell progeny prevents teratoma formation
por: Park, Jongjin, et al.
Publicado: (2022)

Genome-Wide Screening in Human Embryonic Stem Cells Highlights the Hippo Signaling Pathway as Granting Synthetic Viability in ATM Deficiency
por: Viner-Breuer, Ruth, et al.
Publicado: (2023)

In vivo reprogrammed pluripotent stem cells from teratomas share analogous properties with their in vitro counterparts
por: Choi, Hyun Woo, et al.
Publicado: (2015)

The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays
por: Salvatori, Daniela C.F., et al.
Publicado: (2018)

miR-302 regulates pluripotency, teratoma formation and differentiation in stem cells via an AKT1/OCT4-dependent manner
por: Li, H-L, et al.
Publicado: (2016)

pRB-Depleted Pluripotent Stem Cell Retinal Organoids Recapitulate Cell State Transitions of Retinoblastoma Development and Suggest an Important Role for pRB in Retinal Cell Differentiation
por: Rozanska, Agata, et al.
Publicado: (2022)

Conditionally replicating adenovirus prevents pluripotent stem cell–derived teratoma by specifically eliminating undifferentiated cells
por: Mitsui, Kaoru, et al.
Publicado: (2015)

Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas
por: Riegler, Johannes, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_h9omg4vack2hnri692e88sjiff