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The Presence of Genetic Mutations at Key Loci Predicts Progression to Esophageal Adenocarcinoma in Barrett's Esophagus
OBJECTIVES: Risk stratification in Barrett's esophagus (BE) is challenging. We evaluated the ability of a panel of genetic markers to predict progression to high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC). METHODS: In this case–control study, we assessed a measure of genetic insta...
Autores principales: | Eluri, Swathi, Brugge, William R, Daglilar, Ebubekir S, Jackson, Sara A, Styn, Mindi A, Callenberg, Keith M, Welch, Derek C, Barr, Todd M, Duits, Lucas C, Bergman, Jacques J, Shaheen, Nicholas J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471888/ https://www.ncbi.nlm.nih.gov/pubmed/26010308 http://dx.doi.org/10.1038/ajg.2015.152 |
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