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Casein kinase 1 controls the activation threshold of an α-arrestin by multisite phosphorylation of the interdomain hinge

α-Arrestins play a key role as trafficking adaptors in both yeast and mammals. The yeast Rim8/Art9 α-arrestin mediates the recruitment of endosomal sorting complex required for transport (ESCRT) to the seven-transmembrane protein Rim21 in the ambient pH signaling RIM pathway. ESCRT is believed to fu...

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Detalles Bibliográficos
Autores principales: Herrador, Antonio, Livas, Daniela, Soletto, Lucía, Becuwe, Michel, Léon, Sébastien, Vincent, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472021/
https://www.ncbi.nlm.nih.gov/pubmed/25851600
http://dx.doi.org/10.1091/mbc.E14-11-1552