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Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells

Glycogen synthase kinase-3 (Gsk-3) is a key regulator of multiple signal transduction pathways. Recently we described a novel role for Gsk-3 in the regulation of DNA methylation at imprinted loci in mouse embryonic stem cells (ESCs), suggesting that epigenetic changes regulated by Gsk-3 are likely a...

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Detalles Bibliográficos
Autores principales: Meredith, Gavin D., D'Ippolito, Anthony, Dudas, Miroslav, Zeidner, Leigh C., Hostetter, Logan, Faulds, Kelsie, Arnold, Thomas H., Popkie, Anthony P., Doble, Bradley W., Marnellos, George, Adams, Christopher, Wang, Yulei, Phiel, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472022/
https://www.ncbi.nlm.nih.gov/pubmed/25833708
http://dx.doi.org/10.1091/mbc.E15-01-0013