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Insulin exerts direct, IGF-1 independent actions in growth plate chondrocytes

Insufficient insulin production or action in diabetic states is associated with growth retardation and impaired bone healing, while the underling mechanisms are unknown. In this study, we sought to define the role of insulin signaling in the growth plate. Insulin treatment of embryonic metatarsal bo...

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Detalles Bibliográficos
Autores principales:	Zhang, Fengjie, He, Qiling, Tsang, Wing Pui, Garvey, W Timothy, Chan, Wai Yee, Wan, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472128/ https://www.ncbi.nlm.nih.gov/pubmed/26273523 http://dx.doi.org/10.1038/boneres.2014.12

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