Cargando…

Nrf2 is required for normal postnatal bone acquisition in mice

A large body of literature suggests that bone metabolism is susceptible to the ill effects of reactive species that accumulate in the body and cause cellular dysfunction. One of the body’s front lines in defense against such damage is the transcription factor, Nrf2. This transcription factor regulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Jung-Hyun, Singhal, Vandana, Biswal, Shyam, Thimmulappa, Rajesh K, DiGirolamo, Douglas J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472135/ https://www.ncbi.nlm.nih.gov/pubmed/26273528 http://dx.doi.org/10.1038/boneres.2014.33

Ejemplares similares

Disruption of Nrf2, a Key Inducer of Antioxidant Defenses, Attenuates ApoE-Mediated Atherosclerosis in Mice
por: Sussan, Thomas E., et al.
Publicado: (2008)

Administration of soluble activin receptor 2B increases bone and muscle mass in a mouse model of osteogenesis imperfecta
por: DiGirolamo, Douglas J., et al.
Publicado: (2015)

Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress
por: Mercado, Nicolas, et al.
Publicado: (2011)

Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer
por: Singh, Anju, et al.
Publicado: (2006)

Upregulation of TLR1, TLR2, TLR4, and IRAK-2 Expression During ML-1 Cell Differentiation to Macrophages: Role in the Potentiation of Cellular Responses to LPS and LTA
por: Traore, Kassim, et al.
Publicado: (2012)

Network Inference Algorithms Elucidate Nrf2 Regulation of Mouse Lung Oxidative Stress
por: Taylor, Ronald C., et al.
Publicado: (2008)

Prolonged sulforaphane treatment does not enhance tumorigenesis in oncogenic K-ras and xenograft mouse models of lung cancer
por: Kombairaju, Ponvijay, et al.
Publicado: (2012)

Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial
por: Wise, Robert A., et al.
Publicado: (2016)

Correction: Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial
por: Wise, Robert A., et al.
Publicado: (2017)

Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation
por: Zhao, Ming, et al.
Publicado: (2002)

PHOSPHORYLATION OF ULK1 AT S555 IS REQUIRED FOR METABOLIC ADAPTATIONS TO CALORIC RESTRICTION
por: Drake, Joshua, et al.
Publicado: (2022)

Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition
por: Riddle, Ryan C., et al.
Publicado: (2013)

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells
por: Lotz, Michael, et al.
Publicado: (2006)

Reward, Context, and Human Behaviour
por: Blaukopf, Clare L., et al.
Publicado: (2007)

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice
por: Rangasamy, Tirumalai, et al.
Publicado: (2005)

Exposure to Electronic Cigarettes Impairs Pulmonary Anti-Bacterial and Anti-Viral Defenses in a Mouse Model
por: Sussan, Thomas E., et al.
Publicado: (2015)

Metastasis of hormone-independent breast cancer to lung and bone is decreased by α-difluoromethylornithine treatment
por: Richert, Monica M, et al.
Publicado: (2005)

Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system
por: Gao, Meixia, et al.
Publicado: (2011)

ERRγ Is Not Required for Skeletal Development but Is a RUNX2-Dependent Negative Regulator of Postnatal Bone Formation in Male Mice
por: Cardelli, Marco, et al.
Publicado: (2014)

Targeted Inhibition of Anti-Inflammatory Regulator Nrf2 Results in Breast Cancer Retardation In Vitro and In Vivo
por: Bovilla, Venugopal R., et al.
Publicado: (2021)

Aerobic Glycolysis Is Required for Spatial Memory Acquisition But Not Memory Retrieval in Mice
por: Harris, Richard A., et al.
Publicado: (2019)

Congenital and Postnatal CMV and EBV Acquisition in HIV-Infected Zimbabwean Infants
por: Gumbo, Hlanai, et al.
Publicado: (2014)

116. Role of Maternal Antibodies in Protection Against Postnatal Cytomegalovirus Acquisition
por: Saccoccio, Frances, et al.
Publicado: (2018)

Antiviral, immunomodulatory, and anticoagulant effects of quercetin and its derivatives: Potential role in prevention and management of COVID-19
por: Manjunath, Souparnika H., et al.
Publicado: (2022)

NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression
por: Sánchez-de-Diego, Cristina, et al.
Publicado: (2020)

Constitutive Activation of Gli2 Impairs Bone Formation in Postnatal Growing Mice
por: Joeng, Kyu Sang, et al.
Publicado: (2013)

Oxidative Stress Mechanisms in the Pathogenesis of Environmental Lung Diseases
por: Thimmulappa, Rajesh K., et al.
Publicado: (2019)

Design and development of innovative microparticulate/nanoparticulate inhalable dry powders of a novel synthetic trifluorinated chalcone derivative and Nrf2 agonist
por: Muralidharan, Priya, et al.
Publicado: (2020)

Palmitoyl Acyltransferase, Zdhhc13, Facilitates Bone Mass Acquisition by Regulating Postnatal Epiphyseal Development and Endochondral Ossification: A Mouse Model
por: Song, I-Wen, et al.
Publicado: (2014)

Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation
por: Kumar, Anil, et al.
Publicado: (2018)

Genetic silencing of Nrf2 enhances X-ROS in dysferlin-deficient muscle
por: Kombairaju, Ponvijay, et al.
Publicado: (2014)

Compartmentalization of anti-oxidant and anti-inflammatory gene expression in current and former smokers with COPD
por: Sidhaye, Venkataramana K., et al.
Publicado: (2019)

Prenatal and postnatal echocardiography in NT fetuses with normal karyotype
por: Emami-Moghaddam, Abdolrahman, et al.
Publicado: (2019)

Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration
por: Arnold, W. David, et al.
Publicado: (2016)

Copper Requirement and Acquisition by Marine Microalgae
por: Kong, Liangliang
Publicado: (2022)

CHIP regulates skeletal development and postnatal bone growth
por: Wang, Wenbo, et al.
Publicado: (2020)

Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys
por: Kaur, Amitinder, et al.
Publicado: (2018)

Dissection of the Auditory Bulla in Postnatal Mice: Isolation of the Middle Ear Bones and Histological Analysis
por: Sakamoto, Ayako, et al.
Publicado: (2017)

Phospholipase Cγ2 Is Required for Luminal Expansion of the Epididymal Duct during Postnatal Development in Mice
por: Ichise, Hirotake, et al.
Publicado: (2016)

Nrf2 regulates gene-environment interactions in an animal model of intrauterine inflammation: Implications for preterm birth and prematurity
por: Sussan, Thomas E., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sqbcl4b764kj4g4nhjnalfhnlt