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LRP6 in mesenchymal stem cells is required for bone formation during bone growth and bone remodeling

Lipoprotein receptor-related protein 6 (LRP6) plays a critical role in skeletal development and homeostasis in adults. However, the role of LRP6 in mesenchymal stem cells (MSCs), skeletal stem cells that give rise to osteoblastic lineage, is unknown. In this study, we generated mice lacking LRP6 exp...

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Detalles Bibliográficos
Autores principales:	Li, Changjun, Williams, Bart O, Cao, Xu, Wan, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472141/ https://www.ncbi.nlm.nih.gov/pubmed/26273519 http://dx.doi.org/10.1038/boneres.2014.6

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