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The frequency of CYP2C19 genetic polymorphisms in Russian patients with peptic ulcers treated with proton pump inhibitors

INTRODUCTION: Proton pump inhibitors, which are widely used as acid-inhibitory agents for the treatment of peptic ulcers, are mainly metabolized by 2C19 isoenzyme of cytochrome P450 (CYP2C19). CYP2C19 has genetic polymorphisms, associated with extensive, poor, intermediate or ultra-rapid metabolism...

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Detalles Bibliográficos
Autores principales:	Sychev, DA, Denisenko, NP, Sizova, ZM, Grachev, AV, Velikolug, KA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472152/ https://www.ncbi.nlm.nih.gov/pubmed/26109874 http://dx.doi.org/10.2147/PGPM.S78986

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