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Brave new epigenomes: the dawn of epigenetic engineering
New methods for epigenome editing now make it possible to manipulate the epigenome in living cells with unprecedented specificity and efficiency. These ground-breaking approaches are beginning to yield novel insights into the function of individual chromatin marks in the context of cellular phenotyp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472160/ https://www.ncbi.nlm.nih.gov/pubmed/26089986 http://dx.doi.org/10.1186/s13073-015-0185-8 |
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author | Köferle, Anna Stricker, Stefan H. Beck, Stephan |
author_facet | Köferle, Anna Stricker, Stefan H. Beck, Stephan |
author_sort | Köferle, Anna |
collection | PubMed |
description | New methods for epigenome editing now make it possible to manipulate the epigenome in living cells with unprecedented specificity and efficiency. These ground-breaking approaches are beginning to yield novel insights into the function of individual chromatin marks in the context of cellular phenotype. |
format | Online Article Text |
id | pubmed-4472160 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-44721602015-06-19 Brave new epigenomes: the dawn of epigenetic engineering Köferle, Anna Stricker, Stefan H. Beck, Stephan Genome Med Comment New methods for epigenome editing now make it possible to manipulate the epigenome in living cells with unprecedented specificity and efficiency. These ground-breaking approaches are beginning to yield novel insights into the function of individual chromatin marks in the context of cellular phenotype. BioMed Central 2015-08-04 /pmc/articles/PMC4472160/ /pubmed/26089986 http://dx.doi.org/10.1186/s13073-015-0185-8 Text en © Köferle et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Comment Köferle, Anna Stricker, Stefan H. Beck, Stephan Brave new epigenomes: the dawn of epigenetic engineering |
title | Brave new epigenomes: the dawn of epigenetic engineering |
title_full | Brave new epigenomes: the dawn of epigenetic engineering |
title_fullStr | Brave new epigenomes: the dawn of epigenetic engineering |
title_full_unstemmed | Brave new epigenomes: the dawn of epigenetic engineering |
title_short | Brave new epigenomes: the dawn of epigenetic engineering |
title_sort | brave new epigenomes: the dawn of epigenetic engineering |
topic | Comment |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472160/ https://www.ncbi.nlm.nih.gov/pubmed/26089986 http://dx.doi.org/10.1186/s13073-015-0185-8 |
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