Cargando…

Brave new epigenomes: the dawn of epigenetic engineering

New methods for epigenome editing now make it possible to manipulate the epigenome in living cells with unprecedented specificity and efficiency. These ground-breaking approaches are beginning to yield novel insights into the function of individual chromatin marks in the context of cellular phenotyp...

Descripción completa

Detalles Bibliográficos
Autores principales: Köferle, Anna, Stricker, Stefan H., Beck, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472160/
https://www.ncbi.nlm.nih.gov/pubmed/26089986
http://dx.doi.org/10.1186/s13073-015-0185-8
_version_ 1782377011705020416
author Köferle, Anna
Stricker, Stefan H.
Beck, Stephan
author_facet Köferle, Anna
Stricker, Stefan H.
Beck, Stephan
author_sort Köferle, Anna
collection PubMed
description New methods for epigenome editing now make it possible to manipulate the epigenome in living cells with unprecedented specificity and efficiency. These ground-breaking approaches are beginning to yield novel insights into the function of individual chromatin marks in the context of cellular phenotype.
format Online
Article
Text
id pubmed-4472160
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-44721602015-06-19 Brave new epigenomes: the dawn of epigenetic engineering Köferle, Anna Stricker, Stefan H. Beck, Stephan Genome Med Comment New methods for epigenome editing now make it possible to manipulate the epigenome in living cells with unprecedented specificity and efficiency. These ground-breaking approaches are beginning to yield novel insights into the function of individual chromatin marks in the context of cellular phenotype. BioMed Central 2015-08-04 /pmc/articles/PMC4472160/ /pubmed/26089986 http://dx.doi.org/10.1186/s13073-015-0185-8 Text en © Köferle et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Köferle, Anna
Stricker, Stefan H.
Beck, Stephan
Brave new epigenomes: the dawn of epigenetic engineering
title Brave new epigenomes: the dawn of epigenetic engineering
title_full Brave new epigenomes: the dawn of epigenetic engineering
title_fullStr Brave new epigenomes: the dawn of epigenetic engineering
title_full_unstemmed Brave new epigenomes: the dawn of epigenetic engineering
title_short Brave new epigenomes: the dawn of epigenetic engineering
title_sort brave new epigenomes: the dawn of epigenetic engineering
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472160/
https://www.ncbi.nlm.nih.gov/pubmed/26089986
http://dx.doi.org/10.1186/s13073-015-0185-8
work_keys_str_mv AT koferleanna bravenewepigenomesthedawnofepigeneticengineering
AT strickerstefanh bravenewepigenomesthedawnofepigeneticengineering
AT beckstephan bravenewepigenomesthedawnofepigeneticengineering