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Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells

Luteolin and apigenin are dietary flavones and exhibit a broad spectrum of biological activities including antioxidant, anti-inflammatory, anti-cancer and neuroprotective effects. The lipid peroxidation product 4-hydroxy-2-nonenal (4-HNE) has been implicated as a causative agent in the development o...

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Detalles Bibliográficos
Autores principales:	Wu, Pei-Shan, Yen, Jui-Hung, Kou, Mei-Chun, Wu, Ming-Jiuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472230/ https://www.ncbi.nlm.nih.gov/pubmed/26087007 http://dx.doi.org/10.1371/journal.pone.0130599

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