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Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?
Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472269/ https://www.ncbi.nlm.nih.gov/pubmed/26084781 http://dx.doi.org/10.1186/s13054-015-0958-x |
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author | Corrêa, Thiago Domingos Jakob, Stephan Matthias Takala, Jukka |
author_facet | Corrêa, Thiago Domingos Jakob, Stephan Matthias Takala, Jukka |
author_sort | Corrêa, Thiago Domingos |
collection | PubMed |
description | Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasing arterial blood pressure improved sublingual microcirculation parameters, no concomitant improvement in systemic tissue perfusion indicators was found. Here, we discuss why resuscitation targets may need to be individualized, taking into account the patient’s baseline condition, and present directions for future research in this field. |
format | Online Article Text |
id | pubmed-4472269 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-44722692015-06-19 Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? Corrêa, Thiago Domingos Jakob, Stephan Matthias Takala, Jukka Crit Care Commentary Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasing arterial blood pressure improved sublingual microcirculation parameters, no concomitant improvement in systemic tissue perfusion indicators was found. Here, we discuss why resuscitation targets may need to be individualized, taking into account the patient’s baseline condition, and present directions for future research in this field. BioMed Central 2015-06-18 2015 /pmc/articles/PMC4472269/ /pubmed/26084781 http://dx.doi.org/10.1186/s13054-015-0958-x Text en © Corrêa et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Commentary Corrêa, Thiago Domingos Jakob, Stephan Matthias Takala, Jukka Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? |
title | Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? |
title_full | Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? |
title_fullStr | Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? |
title_full_unstemmed | Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? |
title_short | Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? |
title_sort | arterial blood pressure targets in septic shock: is it time to move to an individualized approach? |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472269/ https://www.ncbi.nlm.nih.gov/pubmed/26084781 http://dx.doi.org/10.1186/s13054-015-0958-x |
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