Cargando…

Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?

Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasi...

Descripción completa

Detalles Bibliográficos
Autores principales: Corrêa, Thiago Domingos, Jakob, Stephan Matthias, Takala, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472269/
https://www.ncbi.nlm.nih.gov/pubmed/26084781
http://dx.doi.org/10.1186/s13054-015-0958-x
_version_ 1782377034340630528
author Corrêa, Thiago Domingos
Jakob, Stephan Matthias
Takala, Jukka
author_facet Corrêa, Thiago Domingos
Jakob, Stephan Matthias
Takala, Jukka
author_sort Corrêa, Thiago Domingos
collection PubMed
description Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasing arterial blood pressure improved sublingual microcirculation parameters, no concomitant improvement in systemic tissue perfusion indicators was found. Here, we discuss why resuscitation targets may need to be individualized, taking into account the patient’s baseline condition, and present directions for future research in this field.
format Online
Article
Text
id pubmed-4472269
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-44722692015-06-19 Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? Corrêa, Thiago Domingos Jakob, Stephan Matthias Takala, Jukka Crit Care Commentary Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasing arterial blood pressure improved sublingual microcirculation parameters, no concomitant improvement in systemic tissue perfusion indicators was found. Here, we discuss why resuscitation targets may need to be individualized, taking into account the patient’s baseline condition, and present directions for future research in this field. BioMed Central 2015-06-18 2015 /pmc/articles/PMC4472269/ /pubmed/26084781 http://dx.doi.org/10.1186/s13054-015-0958-x Text en © Corrêa et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Corrêa, Thiago Domingos
Jakob, Stephan Matthias
Takala, Jukka
Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?
title Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?
title_full Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?
title_fullStr Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?
title_full_unstemmed Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?
title_short Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?
title_sort arterial blood pressure targets in septic shock: is it time to move to an individualized approach?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472269/
https://www.ncbi.nlm.nih.gov/pubmed/26084781
http://dx.doi.org/10.1186/s13054-015-0958-x
work_keys_str_mv AT correathiagodomingos arterialbloodpressuretargetsinsepticshockisittimetomovetoanindividualizedapproach
AT jakobstephanmatthias arterialbloodpressuretargetsinsepticshockisittimetomovetoanindividualizedapproach
AT takalajukka arterialbloodpressuretargetsinsepticshockisittimetomovetoanindividualizedapproach