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A 40-bp VNTR polymorphism in the 3′-untranslated region of DAT1/SLC6A3 is associated with ADHD but not with alcoholism
BACKGROUND: ADHD and alcoholism are psychiatric diseases with pathophysiology related to dopamine system. DAT1 belongs to the SLC6 family of transporters and is involved in the regulation of extracellular dopamine levels. A 40 bp variable number tandem repeat (VNTR) polymorphism in the 3′-untranslat...
Autores principales: | Šerý, Omar, Paclt, Ivo, Drtílková, Ivana, Theiner, Pavel, Kopečková, Marta, Zvolský, Petr, Balcar, Vladimir J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472402/ https://www.ncbi.nlm.nih.gov/pubmed/26058807 http://dx.doi.org/10.1186/s12993-015-0066-8 |
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