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Differential Effects of Tacrolimus versus Sirolimus on the Proliferation, Activation and Differentiation of Human B Cells

The direct effect of immunosuppressive drugs calcineurin inhibitor (Tacrolimus, TAC) and mTOR inhibitor (Sirolimus, SRL) on B cell activation, differentiation and proliferation is not well documented. Purified human B cells from healthy volunteers were stimulated through the B Cell Receptor with Ant...

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Detalles Bibliográficos
Autores principales:	Traitanon, Opas, Mathew, James M, La Monica, Giovanna, Xu, Luting, Mas, Valeria, Gallon, Lorenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472515/ https://www.ncbi.nlm.nih.gov/pubmed/26087255 http://dx.doi.org/10.1371/journal.pone.0129658

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