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Hemophilia A in a Senior Patient: A Case Report of Spinal Epidural Hematoma as First Presentation

Hemophilia A is a hereditary coagulation disorder. Most cases are diagnosed at birth or at least during childhood. A spontaneous spinal epidural hematoma was developed in a 74-year-old male patient who hadn't had a family or past medical history of bleeding disorders. On magnetic resonance imag...

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Autores principales: Ahn, Dong Ki, Jung, Woo Shik, Lee, Jae Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Spine Surgery 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472596/
https://www.ncbi.nlm.nih.gov/pubmed/26097663
http://dx.doi.org/10.4184/asj.2015.9.3.452
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author Ahn, Dong Ki
Jung, Woo Shik
Lee, Jae Il
author_facet Ahn, Dong Ki
Jung, Woo Shik
Lee, Jae Il
author_sort Ahn, Dong Ki
collection PubMed
description Hemophilia A is a hereditary coagulation disorder. Most cases are diagnosed at birth or at least during childhood. A spontaneous spinal epidural hematoma was developed in a 74-year-old male patient who hadn't had a family or past medical history of bleeding disorders. On magnetic resonance imaging, epidural hematoma at L1-2 was accompanied by spinal stenosis at L4-5 and spondylolytic spondylolisthesis at L5. Hematoma evacuation and surgery for distal lumbar lesions were performed at once. After transient improvement, complete paraplegia was developed due to redevelopment of large epidural hematomas at L1-2 and L4-S1 which blocked epidural canal completely. Emergency evacuation was performed and we got to know that he had a hemophilia A. Factor VIII was 28% of normal value. Mild type hemophilia A could have not been diagnosed until adulthood. Factor VIII should have been replaced before the surgical decompression.
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spelling pubmed-44725962015-06-19 Hemophilia A in a Senior Patient: A Case Report of Spinal Epidural Hematoma as First Presentation Ahn, Dong Ki Jung, Woo Shik Lee, Jae Il Asian Spine J Case Report Hemophilia A is a hereditary coagulation disorder. Most cases are diagnosed at birth or at least during childhood. A spontaneous spinal epidural hematoma was developed in a 74-year-old male patient who hadn't had a family or past medical history of bleeding disorders. On magnetic resonance imaging, epidural hematoma at L1-2 was accompanied by spinal stenosis at L4-5 and spondylolytic spondylolisthesis at L5. Hematoma evacuation and surgery for distal lumbar lesions were performed at once. After transient improvement, complete paraplegia was developed due to redevelopment of large epidural hematomas at L1-2 and L4-S1 which blocked epidural canal completely. Emergency evacuation was performed and we got to know that he had a hemophilia A. Factor VIII was 28% of normal value. Mild type hemophilia A could have not been diagnosed until adulthood. Factor VIII should have been replaced before the surgical decompression. Korean Society of Spine Surgery 2015-06 2015-06-08 /pmc/articles/PMC4472596/ /pubmed/26097663 http://dx.doi.org/10.4184/asj.2015.9.3.452 Text en Copyright © 2015 by Korean Society of Spine Surgery http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ahn, Dong Ki
Jung, Woo Shik
Lee, Jae Il
Hemophilia A in a Senior Patient: A Case Report of Spinal Epidural Hematoma as First Presentation
title Hemophilia A in a Senior Patient: A Case Report of Spinal Epidural Hematoma as First Presentation
title_full Hemophilia A in a Senior Patient: A Case Report of Spinal Epidural Hematoma as First Presentation
title_fullStr Hemophilia A in a Senior Patient: A Case Report of Spinal Epidural Hematoma as First Presentation
title_full_unstemmed Hemophilia A in a Senior Patient: A Case Report of Spinal Epidural Hematoma as First Presentation
title_short Hemophilia A in a Senior Patient: A Case Report of Spinal Epidural Hematoma as First Presentation
title_sort hemophilia a in a senior patient: a case report of spinal epidural hematoma as first presentation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472596/
https://www.ncbi.nlm.nih.gov/pubmed/26097663
http://dx.doi.org/10.4184/asj.2015.9.3.452
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