Cladribine Exposure Results in a Sustained Modulation of the Cytokine Response in Human Peripheral Blood Mononuclear Cells

BACKGROUND AND OBJECTIVES: Cladribine is a cytotoxic drug which ameliorates the clinical course of relapsing-remitting multiple sclerosis. In addition to cytotoxicity, the mode of action may include immunomodulatory mechanisms. This in vitro study was designed to investigate cladribine’s effects on...

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Detalles Bibliográficos
Autores principales: Korsen, Melanie, Bragado Alonso, Sara, Peix, Lizzy, Bröker, Barbara M., Dressel, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472752/
https://www.ncbi.nlm.nih.gov/pubmed/26086440
http://dx.doi.org/10.1371/journal.pone.0129182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472752/
https://www.ncbi.nlm.nih.gov/pubmed/26086440
http://dx.doi.org/10.1371/journal.pone.0129182

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