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Cladribine Exposure Results in a Sustained Modulation of the Cytokine Response in Human Peripheral Blood Mononuclear Cells
BACKGROUND AND OBJECTIVES: Cladribine is a cytotoxic drug which ameliorates the clinical course of relapsing-remitting multiple sclerosis. In addition to cytotoxicity, the mode of action may include immunomodulatory mechanisms. This in vitro study was designed to investigate cladribine’s effects on...
Autores principales: | Korsen, Melanie, Bragado Alonso, Sara, Peix, Lizzy, Bröker, Barbara M., Dressel, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472752/ https://www.ncbi.nlm.nih.gov/pubmed/26086440 http://dx.doi.org/10.1371/journal.pone.0129182 |
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