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Gene Expression Signature in Adipose Tissue of Acromegaly Patients

To study the effect of chronic excess growth hormone on adipose tissue, we performed RNA sequencing in adipose tissue biopsies from patients with acromegaly (n = 7) or non-functioning pituitary adenomas (n = 11). The patients underwent clinical and metabolic profiling including assessment of HOMA-IR...

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Detalles Bibliográficos
Autores principales: Hochberg, Irit, Tran, Quynh T., Barkan, Ariel L., Saltiel, Alan R., Chandler, William F., Bridges, Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472931/
https://www.ncbi.nlm.nih.gov/pubmed/26087292
http://dx.doi.org/10.1371/journal.pone.0129359