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Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice
AIMS/HYPOTHESIS: The identification of novel targets that stimulate endogenous regeneration of beta cells would represent a significant advance in the treatment of patients with diabetes. The betatrophin hypothesis suggests that increased expression of angiopoietin-like protein 8 (ANGPTL8) induces d...
Autores principales: | Cox, Aaron R., Lam, Carol J., Bonnyman, Claire W., Chavez, Julia, Rios, Jacqueline S., Kushner, Jake A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473078/ https://www.ncbi.nlm.nih.gov/pubmed/25917759 http://dx.doi.org/10.1007/s00125-015-3590-z |
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