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Polymorphisms in the glucocorticoid receptor gene and in the glucocorticoid-induced transcript 1 gene are associated with disease activity and response to glucocorticoid bridging therapy in rheumatoid arthritis
Glucocorticoids (GC) are widely used in rheumatoid arthritis (RA). Ongoing active disease due to GC resistance may unfavorably influence long-term disease outcome in RA. We studied the association between the presence of glucocorticoid receptor (GR) and glucocorticoid-induced transcript 1 (GLCCI1) g...
Autores principales: | Quax, R. A. M., Koper, J. W., Huisman, A. M., Weel, A., Hazes, J. M. W., Lamberts, S. W. J., Feelders, R. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473091/ https://www.ncbi.nlm.nih.gov/pubmed/25724472 http://dx.doi.org/10.1007/s00296-015-3235-z |
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