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Measles in Canada Between 2002 and 2013

Background. In 1994, Canada committed to eliminate measles by the year 2000. This report presents the epidemiology of measles in Canada between 2002 and 2013 and its implications in sustaining measles elimination. Methods. Cases included individuals reported to the Canadian Measles and Rubella Surve...

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Autores principales: De Serres, Gaston, Desai, Shalini, Shane, Amanda, Hiebert, Joanne, Ouakki, Manale, Severini, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473108/
https://www.ncbi.nlm.nih.gov/pubmed/26110163
http://dx.doi.org/10.1093/ofid/ofv048
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author De Serres, Gaston
Desai, Shalini
Shane, Amanda
Hiebert, Joanne
Ouakki, Manale
Severini, Alberto
author_facet De Serres, Gaston
Desai, Shalini
Shane, Amanda
Hiebert, Joanne
Ouakki, Manale
Severini, Alberto
author_sort De Serres, Gaston
collection PubMed
description Background. In 1994, Canada committed to eliminate measles by the year 2000. This report presents the epidemiology of measles in Canada between 2002 and 2013 and its implications in sustaining measles elimination. Methods. Cases included individuals reported to the Canadian Measles and Rubella Surveillance System with confirmed measles. Results. In Canada, 1171 cases of measles were reported between 2002 and 2013 (incidence 0.29 cases per 100 000 population). The annual number of cases ranged from 6 to 752. The majority of cases were unvaccinated (63%) or had an unknown vaccination status (19%). The median age of cases was 14.4 years (range, <1 to 63 years) globally and 14 years when excluding the 2011 outbreak in Quebec where 68% of the 678 cases were 10 to 19 years old. With the exclusion of this outbreak, the incidence was highest in infants (1.0 per 100 000), lower but fairly similar between 1 and 19 years of age (0.2 to 0.4 per 100 000), and there was a substantial decline between 20 and 39 years of age (0.1 per 100 000). There was a significant trend towards a greater annual number of importations over the period. Although importations resulted in no transmission sustained for ≥12 months, 5 chains of transmission had >30 cases. The effective reproductive number between 2002 and 2013 was estimated at 0.86 (95% confidence interval, .81–.92). Conclusions. Canada has maintained elimination between 2002 and 2013, but additional efforts are needed to reduce the proportion of unimmunized individuals and respond to importation events.
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spelling pubmed-44731082015-06-24 Measles in Canada Between 2002 and 2013 De Serres, Gaston Desai, Shalini Shane, Amanda Hiebert, Joanne Ouakki, Manale Severini, Alberto Open Forum Infect Dis Major Articles Background. In 1994, Canada committed to eliminate measles by the year 2000. This report presents the epidemiology of measles in Canada between 2002 and 2013 and its implications in sustaining measles elimination. Methods. Cases included individuals reported to the Canadian Measles and Rubella Surveillance System with confirmed measles. Results. In Canada, 1171 cases of measles were reported between 2002 and 2013 (incidence 0.29 cases per 100 000 population). The annual number of cases ranged from 6 to 752. The majority of cases were unvaccinated (63%) or had an unknown vaccination status (19%). The median age of cases was 14.4 years (range, <1 to 63 years) globally and 14 years when excluding the 2011 outbreak in Quebec where 68% of the 678 cases were 10 to 19 years old. With the exclusion of this outbreak, the incidence was highest in infants (1.0 per 100 000), lower but fairly similar between 1 and 19 years of age (0.2 to 0.4 per 100 000), and there was a substantial decline between 20 and 39 years of age (0.1 per 100 000). There was a significant trend towards a greater annual number of importations over the period. Although importations resulted in no transmission sustained for ≥12 months, 5 chains of transmission had >30 cases. The effective reproductive number between 2002 and 2013 was estimated at 0.86 (95% confidence interval, .81–.92). Conclusions. Canada has maintained elimination between 2002 and 2013, but additional efforts are needed to reduce the proportion of unimmunized individuals and respond to importation events. Oxford University Press 2015-04-15 /pmc/articles/PMC4473108/ /pubmed/26110163 http://dx.doi.org/10.1093/ofid/ofv048 Text en © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Major Articles
De Serres, Gaston
Desai, Shalini
Shane, Amanda
Hiebert, Joanne
Ouakki, Manale
Severini, Alberto
Measles in Canada Between 2002 and 2013
title Measles in Canada Between 2002 and 2013
title_full Measles in Canada Between 2002 and 2013
title_fullStr Measles in Canada Between 2002 and 2013
title_full_unstemmed Measles in Canada Between 2002 and 2013
title_short Measles in Canada Between 2002 and 2013
title_sort measles in canada between 2002 and 2013
topic Major Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473108/
https://www.ncbi.nlm.nih.gov/pubmed/26110163
http://dx.doi.org/10.1093/ofid/ofv048
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