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Efavirenz Has the Highest Anti-Proliferative Effect of Non-Nucleoside Reverse Transcriptase Inhibitors against Pancreatic Cancer Cells

BACKGROUND: Cancer prevention and therapy in HIV-1-infected patients will play an important role in future. The non-nucleoside reverse transcriptase inhibitors (NNRTI) Efavirenz and Nevirapine are cytotoxic against cancer cells in vitro. As other NNRTIs have not been studied so far, all clinically u...

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Detalles Bibliográficos
Autores principales:	Hecht, Markus, Erber, Sonja, Harrer, Thomas, Klinker, Hartwig, Roth, Thomas, Parsch, Hans, Fiebig, Nora, Fietkau, Rainer, Distel, Luitpold V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473268/ https://www.ncbi.nlm.nih.gov/pubmed/26086472 http://dx.doi.org/10.1371/journal.pone.0130277

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