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Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses
CD8(+) T cells directed against conserved viral regions elicit broad immunity against distinct influenza viruses, promote rapid virus elimination and enhanced host recovery. The influenza neuraminidase inhibitor, oseltamivir, is prescribed for therapy and prophylaxis, although it remains unclear how...
Autores principales: | Bird, Nicola L., Olson, Matthew R., Hurt, Aeron C., Oshansky, Christine M., Oh, Ding Yuan, Reading, Patrick C., Chua, Brendon Y., Sun, Yilun, Tang, Li, Handel, Andreas, Jackson, David C., Turner, Stephen J., Thomas, Paul G., Kedzierska, Katherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473273/ https://www.ncbi.nlm.nih.gov/pubmed/26086392 http://dx.doi.org/10.1371/journal.pone.0129768 |
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