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In Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses
Newly emerging influenza A viruses (IAV) pose a major threat to human health by causing seasonal epidemics and/or pandemics, the latter often facilitated by the lack of pre-existing immunity in the general population. Early recognition of candidate pandemic influenza viruses (CPIV) is of crucial imp...
Autores principales: | Schmier, Sonja, Mostafa, Ahmed, Haarmann, Thomas, Bannert, Norbert, Ziebuhr, John, Veljkovic, Veljko, Dietrich, Ursula, Pleschka, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473683/ https://www.ncbi.nlm.nih.gov/pubmed/26091504 http://dx.doi.org/10.1038/srep11434 |
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